In Hardy-Weinberg equilibrium, genotype frequencies in a large, random-mating population with no selection are p^2, 2pq, and q^2. Which option BEST expresses this principle?

• A. Phenotype frequencies equal genotype frequencies
• B. In large, random-mating populations with no selection, p^2, 2pq, q^2
• C. Only p^2 occurs
• D. In any population frequencies must sum to 1, regardless of alleles

Answer: (B)